CLIO · CONTEXT LAYER FOR I/O

AI for science you can check.

IOWarp builds CLIO, open-source software that puts AI agents to work on your scientific data and leaves a record your people can check. It runs on the systems you already operate, from a workstation to a national facility. In AI-driven science, context is part of the system.

THE CLIO SUITE

Start anywhere.
Each piece stands alone.

Choose the product closest to your work. CLIO Agent and CLIO Coder serve people working on scientific data and scientific software; CLIO Kit supplies the scientific tools both share, and CLIO Core runs the context hierarchy underneath.

Flagship Scientific data workspace

For scientists, lab teams, and facility data managers.

Work with files, live streams, visualizations, shared web pages, and LaTeX papers in the desktop app or a browser, on local, cloud, or lab models.

curl -fsSL https://clio.iowarp.ai/install.sh | bash
FIG S.1 · HOW THE CLIO PRODUCTS CONNECTPEOPLE · AGENTS · TOOLS · RUNTIME · DATA
CLIO Agent serves scientific data and papers; CLIO Coder serves scientific software. Both use the models you choose and call tools in CLIO Kit, while CLIO Core stores durable memory and moves context across memory and storage tiers.

WHAT IS THIS?

The whole stack,
from GPU to agent.

IOWarp is the research and engineering team at the Gnosis Research Center, Illinois Tech, that builds CLIO. CLIO, the Context Layer for I/O, is an open-source software stack that connects AI agents to scientific data and the systems that hold it.

It matters because scientific data is only useful with its meaning attached. Point an agent at an HDF5 file or a Slurm queue and it needs the right data, memory that outlasts the session, and a path from a laptop to a national system. CLIO supplies each of those, so an organization can bring AI into its science and hold every change to its own checks.

Adoption is incremental. CLIO Agent, CLIO Coder, CLIO Kit, and CLIO Core each install on their own.

See how the platform fits together

The CLIO platform7 layers · one system
  1. 07Research tooling

    From sources and results to a paper someone can check.

  2. 06Applications

    Science workflows and domain packages built on the stack.

  3. 05Agents and tools
  4. 04Context runtime
  5. 03Storage systems

    Tiered devices, I/O adapters, compression, and data connectors.

  6. 02Operating system

    The Linux I/O path, from asynchronous I/O to kernel modules.

  7. 01Accelerators

    GPU code that reaches the storage hierarchy directly.

ACROSS DISCIPLINES

One agentic framework.
Ready for your science.

CLIO began in materials science, expanded to mechanical engineering simulations when neighboring groups saw it run, and now reaches analytical chemistry, federated earth-science catalogs, and DOE Genesis Mission workflows at Argonne and PNNL. Each discipline keeps the same CLIO backbone while swapping in the tools, domain skills, and checks its workflow demands.

FIG W.1 · Where CLIO fits in a research group’s workflowCLOSED-LOOP SCIENTIFIC WORKFLOW
CLIO handles the reading, data plumbing, code verification, and study records around an experiment; the scientists and their instruments keep the scientific judgment.
DOMAIN PROGRESSION · How one discipline unlocks the nextSELECT A FIELD TO INSPECT THE PATTERN

01 · Where CLIO started

Materials science

Additive manufacturing, X-ray computed tomography, segmentation, and next-experiment planning across instruments and clusters.

THE LAB’S WORKFLOW

Printed specimens move from design to tomography scans and fatigue testing, where process history and volumes have to stay linked.

SWAPPED DOMAIN LAYER · KIT & PLUGINS

wtf-MS and Materio study-planning plugins, HDF5 and Parquet tools, ParaView rendering, and Globus data assimilation.

CONSTANT CLIO BACKBONE

CLIO Agent keeps study questions and observations tied to tool calls; CLIO Core holds the shared part record across stages.

IN THE FIELD

Project stories and collaborations.

Select a collaboration to preview its workflow and inspect how CLIO operates alongside working scientists and facilities.

THE LAUNCH

The full stack
will launch at SC26.

IOWarp at SC26November 15–20, 2026 · McCormick Place, Chicago

IOWarp will launch the full CLIO stack at SC26 in Chicago. The team will present work on simulation monitoring, GPU I/O, storage observability, compressed training data, and agent fleets through workshop presentations, research posters, a conference paper, and an HDF5 birds-of-a-feather session with The HDF Group. The user group will gather around these events, and the Technical Advisory Board will form at the end of November.

MON · NOV 16 · PDSW’26 Workshop

Room W179b

TUE · NOV 17 · Research Posters · Poster Blitz

Skyline Ballroom North Pre-Function

WED · NOV 18 · Papers in Conversation

Room W181abc

THU · NOV 19 · Birds of a Feather

Room W185d

Open source

Read the source.
Run the stack.

The IOWarp team at the Gnosis Research Center builds CLIO in the open, alongside the scientific teams and facilities that put it to work.